

Targeting Healthy Longevity 2025
A Global Conference
2025 Inaugural Session: Draft Healthspan Legislation: the THRIVE Act
Therapeutic Healthspan, Research, Innovation and Enhancement ("THRIVE") Act on regulatory pathways, evidentiary standards and incentives for healthspan products.
Friday, February 28, 2025
11:00 am - 12:30 pm ET

About THL25
What is Targeting Healthy Longevity?
The Kitalys Institute Targeting Healthy Longevity (previously Targeting Metabesity) 2025 will consist of a series of free conference session webinars. The annual conference – focused on preventing and delaying the onset of chronic diseases by slowing and potentially reversing biological aging – brings together leading experts from across disciplines to increase healthspan, the span of life free of chronic diseases and disabilities.
This year’s Inaugural Session – Draft Healthspan Legislation: the THRIVE Act will be introduced on Friday, February 28, 2025. Following precedents such as the 21st Century Cures Act and the Orphan Drug Act, the Kitalys Institute has proposed the THRIVE Act- the Therapeutic Healthspan, Research, Innovation and Validation Enhancement Act, as a framework for stepwise regulatory approval and incentives for healthspan products.
​
Join us for this landmark discussion for stakeholders of the healthy longevity movement, which is the inaugural session of the Targeting Healthy Longevity Conference for 2025. Part 1 will be a ‘fireside chat’ discussing the draft Act with Dr. Alexander Fleming, Founder and President of the Kitalys Institute, and David Fox, Partner at Hogan Lovells, moderated by Thomas Seoh, CEO of Kinexum. Part 2 will be a discussion of the draft Act by a panel of prominent experts to be announced. features a fireside chat with Monica Bertagnolli, MD, Director, National Institutes of Health (NIH), and Victor Dzau, MD, President, National Academy of Medicine (NAM), moderated by Peter Libby, MD, Brigham and Women’s Hospital, Mallinckrodt Professor of Medicine, Harvard Medical School. To learn more about this free conference and to register, click here.
​Our audience cuts across sectors and disciplines for a multi-pronged approach to one of the most important health issues affecting people in all walks of life.
-
Healthcare - Administrators, clinicians, and patient advocates interested in the prevention and delay of illness and aging
-
Preclinical Research - Scientists involved in metabolic, cancer, dementia, cardiovascular and aging-related research
-
Clinical Research - Investigators and healthcare providers involved in chronic non-communicable disease care and prevention
-
Industry - Corporate leaders and startups that are developing pharmaceutical, digital health, nutrition, new business models and other approaches to disease prevention and healthy aging
-
Finance - Funders, payers and investors (including capital markets, philanthropies, government and insurers) in disease prevention and healthy aging
-
Policy and Law - Government regulators, policy makers, elected officials, and advisors involved in Healthspan equity and the future of Healthspan
-
Social Justice - Equity groups, social change agents, and philanthropic organizations interested in broadening access to healthy lifespan
-
​Strategy - Futurists, epidemiologists, social scientists, economists, bioethicists, and others thinking about how to harness emerging science behind Metabesity for global public health
-
Academia - Instructors, administrators, students, and researchers across all fields of longevity, aging and Healthspan
-
Communications - Journalists and marketing professionals who recognize hot topics and emerging trends
-
The Interested Public

Upcoming Events
Session 2: Coming Spring 2025
TBD
Important News
Preempting Chronic Diseases Before They Start: A New Healthcare Focus to Keep People Healthy
A Written Summary by Kitalys Institute, UsAgainstAlzheimers, and Flagship Pioneering
​
2025 Speakers
Inaugural Session: Draft Healthspan Act: the THRIVE Act
Friday, February 28, 2025

Alexander Fleming, MD
Founder and President, Kitalys Institute

Steven Grossman
President, HPS Group

David M. Fox
Partner, Hogan Lovells

Thomas Seoh
Executive Vice President, Kitalys Institute

Eve Herold
Director, Healthspan Action Coalition
Prior Events

A Global Conference
2024 Targeting Healthy Longevity Events
Prior Targeting Healthy Longevity Conferences

The Targeting Healthy Longevity 2023 conference offered a new format of "Rolling Calendar" Webinars. Session 1 included the Annual Fireside Chat with the FDA Commissioner. Session 2 focused on Opportunities & Challenges for Preempting Chronic Diseases. In October, Session 3 targeted the topic of Loneliness and Session 4 rounded out the year with The COSMOS Trials.
Prior Targeting Metabesity Conferences

The Targeting Metabesity 2022 conference took on one of the greatest healthcare challenges and opportunities of the 21st century: the prevention or delay of chronic diseases to achieve healthy longevity for all. This complex objective now appears achievable based on developments in geroscience in recent decades that suggest we may be able to delay, or even reverse, biological aging. This cross-disciplinary conference addresses the abundant opportunities for achieving equitable healthspan and the remaining challenges for converting discoveries into products for the general population.

Targeting Metabesity 2020, held virtually due to the COVID-19 pandemic in October 2020, was broadcast live from Harpers Ferry, WV, and attracted about 1,000 registrants worldwide, with 80 speakers over four days. In addition to the usual stellar collection of scientists, doctors, and representatives of large and emerging companies and capital markets, speakers included the President of the National Academy of Medicine, the Scientific Director of the National Institute on Aging, the Director of the FDA Office of New Drugs, two members of Congress, a member of the U.K. House of Lords Chair of the U.K. All-Party Parliamentary Group for Longevity, Strategic Advisory Group, and several best-selling authors. Also, a new Day 4 was dedicated to an Emerging Company Showcase that featured corporate presentations by two dozen hot emerging 'metabolic' companies, with breakout sessions.
The Targeting Metabesity 2021 conference will further take on one of the greatest healthcare challenges and opportunities of the 21st century: the prevention or delay of chronic diseases to achieve healthy longevity for all. This complex objective now appears achievable based on developments in geroscience in recent decades that suggest we may be able to delay, or even reverse, biological aging. Join us in October 11-14, 2021 both virtually and live in Washington, DC for an even more innovative and cross-disciplinary conference that addresses the abundant opportunities for achieving equitable healthspan and the remaining challenges for converting discoveries into products for the general population.
Prior Metabesity Conferences

The second Metabesity conference, called by Margaretta Colangelo of Deep Knowledge Ventures "one of the most important longevity conferences of the year," was held in Washington, DC in 2019, with a stellar speakers roster that included Richard Hodes, Director of the National Institute on Aging, Gary Gibbons, Director of the National Heart, Lung and Blood Institute, Janet Woodcock, Director of the Center for Drug Evaluation and Research at FDA, Susan Mayne, Director of the Center for Food Safety and Applied Nutrition at FDA, and leaders from geroscience, diabetes, cancer, nutrition, exercise, large and emerging companies, connectivity and loneliness, longevity venture capitalists and other stakeholders.
Together with Professor Lawrence Steinman, former long-time head of the immunology department at Stanford and co-discoverer of the M.S. drug Tysabri, Dr. Fleming organized the inaugural Targeting Metabesity conference in London in 2017. This conference brought together what Alex Zhavoronkov, CEO of A.I. leader, Insilco Medicine, characterized in Forbes as a "staggering" set of speakers, including Oxford professors on the boards of Roche and the Novo Nordisk Foundation, Chair of the Nobel Assembly that selects the Nobel Prize for Medicine or Physiology, Deputy Chief Executive of UK NICE, CEO of the Buck Institute for Research on Aging, and CMO of the CMS under the Obama Administration.
.jpg)